Endocrine Abstracts

The Hypothalamic Pituitary Thyroid (HPT) axis is well-known as a classic endocrine negative feedback loop: increased levels of thyroxine (T4) in the blood are associated with a reduction of thyroid stimulating hormone (TSH) production and vice versa. However, the thyroid hormone (TH) system is sensitive to alterations by a number of endocrine disrupting chemicals (EDCs). Intriguingly, exposure to specific EDCs can decrease the levels of T4 but this might be not followed by the...